But many successful pregnancies do start out with a lower beta hCG level. Wang Q, Zhang R, Jia M, Luo L, Ding C, Li TC, Zhou C. Gynecol Endocrinol. The only patient, although presenting with declined -hCG levels from 133.4 to 64.5 mIU/ml, eventually developed into an ectopic pregnancy. My next was 1430. You'll have to wait until the ultrasound to find out. 2 While mild to moderate cramping can be normal, call your doctor if the cramping is not relieved by over-the-counter pain medications . Nearly 50% (47.4%) of the patients were early miscarriage and the rate of ectopic pregnancy was as high as 9.6%. To examine patients after embryo transfer for predictive influence of the human chorionic gonadotropin (hCG) level on the probability of finishing pregnancy with delivery. Morning sickness or nausea typically start in the second month of pregnancy, so it's not a symptom women normally experience in the 2-week wait after a fresh or frozen embryo transfer. Wu Y, Liu H. Likelihood of live birth with extremely low beta-hCG level 14 days after fresh embryo transfer. Epub 2020 Oct 9. Fertil Steril. Hcg 13 days after transfer was 1389 e2 - 2302 progesterone-17.4. I'd be happy with a healthy singleton. 2017 Jan;33(1):62-66. doi: 10.1080/09513590.2016.1203894. And freq urination becoz i drank lots of water. For women that have had an HCG injection as part of their fertility treatment, the hormone takes about 5-14 days to clear from her system, depending on the dose and the individual woman. In the present study, pregnancy outcomes of patients whose serum -hCG levels were < 300 mIU/ml 14 days after blastocyst transfer were investigated. When an endometrial thickness was 7mm, vaginal progesterone (Crinone, Merck Serono, Germany) was given at 90mg once a day for 5days; following which, blastocysts were transferred on day 6. Vitrification and thawing kits (KitazatoBiophamaCo. Ltd. Shizuoka, Japan) were applied for blastocyst cryopreservation and thawing. This educational content is not medical or diagnostic advice. And congrats and have a happy healthy pregnancy either way. Hello I am 42 years old and this is my first ivf. If positive, serial values of hCG were obtained and transvaginal ultrasound was performed 3 weeks after ET and weekly until fetal cardiac activity was seen. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. We use cookies to improve your experience on this website and so that ads you see online can be tailored to your online browsing interests. However, the serum -hCG levels of patients with live births (median: 196 mIU/ml) was significantly higher than that of patients with non-live births (median: 140 mIU/ml, P=0.0001; Table3). Hi 10 days past day 5 embryo transfer first hCG test 211 is this a good numbers for the first beta test please help me i'm afraid that this is not goo? Federal government websites often end in .gov or .mil. Prediction of pregnancy outcomes is performed with the intent of developing an appropriate clinical follow-up strategy. The other one was smaller. Clinical pregnancy was defined as an intrauterine/extrauterine gestational sac that was detected by ultrasound with positive serum -hCG levels. The hCG level grows exponentially in the course of the 9th to 17th day after an embryo transfer (ET). Probabilities of each type of outcome related to the HCG level are given. Good luck! I read that high HCG can occur when there are abnormalities but it sounds like my numbers are more normal than I thought. Conclusions: The hCG value was 678 (564-815) IU/l1 on the 14th day after ET in pregnancy ended in delivery, 321 (216-477) IU/l on average in abortion, 82 (51-132) IU/l in biochemical pregnancy and 1070 (737-1554) IU/l in multiple pregnancy. Cycles where women underwent IVF with subsequent autologous fresh or frozen embryo transfer (ET), had a serum hCG >5 mIU/mL 8 or 10 days after ET, and had an US performed between 5 0/7 and 6 6/7 weeks that did not demonstrate a viable multiple gestation . 2021 Jul;28(7):1827-1838. doi: 10.1007/s43032-020-00347-8. I was 38 when my twins were born and my MFM suggested that I do all non-invasive screenings plus an early anatomy scan at 16 weeks and then if anything came back abnormal we could elect to do an amnio as I was worried about doing the CVS (though I had assumed I would do it before I got pregnant). 63, Duobao Road, Guangzhou, Guangdong, China, Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, No. Totally 8788 patients with serum -hCG >25mIU/mL 14days after frozen blastocyst transfer were screened and 312(3.5%) of them with low serum -hCG levels (i.e., 5299 mIU/ml) were included in the study. I only placed one embryo because I had genetic tests PGD done prior to transfer. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. Prediction of patients that have had an hCG test other than 14days should be calculated according to the hCG doubling time of 48h, which limits its wider application. An increase of at least 35% in 48 hours in early pregnancy is still considered normal. One hundred eleven patients had positive serum quantitative hCG levels 14 days post-ET; 89/111, or 80.2%, had ongoing pregnancies. My HCG levels 14 days after a frozen embryo transfer was 3700 !!! Poikkeus P, Gissler M, Unkila-Kallio L, Hyden-Granskog C, Tiitinen A. Obstetric and neonatal outcome after single embryo transfer. When this happens, a woman's body begins to produce the pregnancy hormone (hCG) from cells in the developing placenta. This is all very nerve racking. However, my nurse said that some women who carry twins have reported passing "tissue". The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not the user has consented to the use of Cookies. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. When is your ultrasound? I am 41 years old now. Normally, you do your first pregnancy test (HCG blood test) 14 days after embryo transfer. Beta hcg levels after ivf. Analytical cookies are used to understand how visitors interact with the website. I didn't. I am pregnant with identical twin boys! The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. I had it done at Cedar Sinai with Dr. Williams, who has done about 27,000 CVS procedures and has had good results compared to other clinics. statement and Blastocyst transfer was done 5days post-ovulation. The gynae said "tentative congratulations" and also said that it may be just to early to see anything in the second sack but likely not twins. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Does anyone have any insights as to what this might mean (particularly re: singleton vs. I "pray" that both my little babies do well. Slightly: The first HCG level after ivf embryo transfer gives only a rough idea of success. This study was supported by the National Natural Science Foundation of China (No.81801532, to HYL and No.81701518, to YY) and Scientific Research Program of The Third Affiliated Hospital of Guangzhou Medical University (No.2017Q15, to YXW). FOIA If it's doubling, then it means that everything is going as expected. Note that once you confirm, this action cannot be undone. The probability of one child delivery after the transfer of one embryo overdue after prolonged cultivation (96 or 120 hrs) grows with the average and above-average hCG values on the day of the draw. Zhao et al., found that the single -hCG value of 399.5IU/L on day 12 after blastocyst transfer was reliable to predict clinical pregnancy with a PPV of 93.47% and an NPV of 67.61%. Not sure this information really helps you out as I know everyone is different. I know that my numbers are on the low side Please help! The burse said numbers dont provide that info, onlu u/s.so now we just waiting. J Assist Reprod Genet. The study by Stone et al., showed that the doubling times of serum -hCG (-t2) increased from 1.6days on day 12, to a doubling time 3days on day 24 after embryo transfer [11], suggesting that -hCG doubled more quickly in early pregnancy. For patients having an initial -hCG >58.8 mIU/ml, luteal phase support should continue. For the -hCG fold increase over 48h, the cut-off for clinical pregnancy was 1.4 with an AUC of 0.899, a sensitivity of 90.3% and a specificity of 77.8%. Group Black's collective includes Essence, The Shade Room and Naturally Curly. This site needs JavaScript to work properly. I really afraid. hCG levels, IVF. Perform beta hcg test 14 days after embryo transfer. Once I hear a heartbeat on Tue (crossing my fingers), I will do lots of research on this but what many woman are doing on this board sounds reasonable. But if you experience vomiting or nausea during these two weeks . 3 4 Yet, they tend to decrease after the three month mark. I heard hcg doubles every 48 hours, does this apply to whatever baseline we have? Early miscarriage was defined as fetal growth arrest or no cardiac activity that was detected in the gestational sac during the first 12weeks of pregnancy. Your post will be hidden and deleted by moderators. Zhao WE, Li YJ, Ou JP, Sun P, Chen WQ, Liang XY. In the present study, pregnancy outcomes of patients whose serum -hCG levels were<300 mIU/ml 14days after blastocyst transfer were investigated. Were you part of the fertility board? By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Cells from the placenta grow deep into the lining of the uterus, establishing a rich blood supply. Although prior work has attempted to predict pregnancy outcomes by assaying serum -hCG levels after blastocyst transfer, no study has focused on pregnancy outcomes in those with initially low serum -hCG levels. This study sought to investigate pregnancy outcomes of patients with low serum -hCG levels 14days after blastocyst transfer. Certified by Health Quality Agency of Andalusia, Certified Medical Website by the Official College of Physicians of Barcelona, Confianza Online seal of quality and transparency, Busines Adapter certificate in compliance with the LSSI (Spanish Information Society Services Act). If the level was between 300 and 600, the ongoing pregnancy rate was 40% (10/25). It's produced by your placenta after conception. Please help! Fishers exact test was applied when the expected count was <5 or the total sample size was <40. 4 weeks LMP: 5 - 426 mIU/mL. Please be sensitive and kind. Your levels are almost identical to mine. My doctor said that 110 bpm is too low and that many embryos at that level don't progress. The answer here, therefore, is a multinomial variable with four levels. Shamonki et al., confirmed that declining serum -hCG levels almost always led to a failed live birth, although they reported 3 cases of live birth with declined serum -hCG levels in a cohort of 6021 patients [10]. Before The spontaneous miscarriage rate was, therefore, 19.8% (22/111). The https:// ensures that you are connecting to the Rates of biochemical pregnancy loss, ectopic pregnancy, early and late miscarriages, live birth were comparable between the <38years group, and the >38years group (Table1). Retrospective study. Don't obsess. I know I need to wait until ultrasound to REALLY know but I'm curious as to others' experiences (so hard to wait!!!). Reprod Sci. A few previously reported studies investigated the prediction of pregnancy outcomes by serum -hCG levels over various days following vitrified-warmed blastocyst transfer. \). Obstetric and perinatal outcomes of pregnancies according to initial maternal serum HCG concentrations after vitrified-warmed single blastocyst transfer. Unauthorized use of these marks is strictly prohibited. I think I will do CVS but was looking into cell free fetal DNA testing, which is the newest non-invasive screening test. Early Maternal Serum -human Chorionic Gonadotropin Measurements After ICSI in the Prediction of Long-term Pregnancy Outcomes: A Retrospective Cohort Analysis. Used to limit the percentage of requests. 2019;38:45564. After 5 years of trying to conceive without any success, My husband and I had decided to try IVF and we were very lucky to success on the first try. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. If 14 days after the aspiration (ovulation) beta-hCG is negative, there is no implantation. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Epub 2016 Jul 22. A good friend transferred 2 embryos and her levels were only in the 500s after 14 days. The transferred embryos were divided into two groups - early (cultivation 48 and 72 hrs) and prolonged cultivation (PC 96 and 120 hrs). This cookie is set by GDPR Cookie Consent plugin. Normal HCG levels range widely in early pregnancy. Since it is detected in maternal serum as soon as 68days after fertilization, -hCG is widely used in the clinic as a marker of pregnancy. Above 6,000 mIU/ml, the hCG often takes over four days to double. 1993 May;59(5):1081-9. doi: 10.1016/s0015-0282(16)55932-9. 2006;86:162633. My main concern is that high HCG levels early on can be something of concern. Journal of Ovarian Research And finally, no vanishing twin syndrome occurred in the setting of a twin pregnancy, with the notable exception of 14 total miscarriages. My HCG 13 days after my 5 day embryo transfer was over 1,300 and my 16 day post-transfer test showed over 3,500. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. In my case I was transferring 5d embryo, and the hcg level was drawn after 2 weeks, I suppose this is the kinda normal for me? I feel more at ease. Let me share that one of my nurses had a first value of 5.2 and delivered her son! Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. Did you do PGS? Conclusion: Shamonki MI, Frattarelli JL, Bergh PA, Scott RT. The site is secure. Zhang Q, Yan J, Tang R, Gao X, Zhang B, Chen ZJ. CONCLUSIONS: A single HCG reading on day 12 after embryo transfer helps to plan the subsequent follow-up. Nescio, my ultrasound is on Tue, July 19. The spontaneous miscarriage rate was, therefore, 19.8% (22/111). Hello! The data sets used and/or analyzed during the current study are available from the corresponding author on reasonable request. Objective: Powered by DCIP Consulting. In this pregnancy ( transfer of two embryos was recently done on 04/12/18) my hcg level at 11 days after transfer was 1200 and on day 13 4000. One study found that median hCG levels on Day 13 after a fresh embryo transfer were 329 for women with one baby and 544 for women carrying twins. Human chorionic gonadotropin levels after blastocyst transfer are highly predictive of pregnancy outcome. 2016 May 20;(5):CD011537. Contact our team on 0161 300 2737. 3 weeks LMP: 5 - 50 mIU/mL. Asked for Female, 27 Years 2080 Views v. -, Fertil Steril. 2011 Dec;96(6):1362-6. doi: 10.1016/j.fertnstert.2011.09.042. ROC curve analysis showed that a predicted value of -hCG for clinical pregnancy was 58.8 mIU/ml with an area under the ROC curve (AUC) of 0.752, a sensitivity of 95.0% and specificity of 53.5%. After an embryo transfer procedure, it takes around 10-14 days to see the IVF results. Congrats. For patients with decreased -hCG levels, 96.8% (30/31) were biochemical pregnancy loss. Reprod BioMed Online. The .gov means its official. Serum human chorionic gonadotropin level measured 17 days after oocyte retrieval can predict final clinical pregnancy outcomes in IVF/ICSI treatment cycles. Craciunas L, Tsampras N, Coomarasamy A, Raine-Fenning N. Cochrane Database Syst Rev. Many women who feel nauseous say they feel sick to their stomach around two weeks after missing their period. volume13, Articlenumber:132 (2020) The present research possesses the following advantages. In normal conception, -hCG levels are doubled every 48h, and consequently, this increased pattern is applied to discriminate normal pregnancy from a state of pathological pregnancy [1]. You may find out you have one crazy pile of hormone releasing singleton. Allows Litespeed Server to store configurations to improve web performance. Wishing you all the good vibes in the world for your first scan! Day 10: By the 10th to 12th day of development, the blastocyst is fully implanted. Second, the study population in our research included patients with low serum levels of -hCG, whose transferred embryos may be less potent than those from patients having normal -hCG levels. 6 weeks LMP: 1,080 . Yadid IM, Criscuolo TS, Santos JF, Giordano LA. I did a blood test two weeks after 5d frozen embryo transfer. Many women on this board (mused included) have done the NIPT with twins at the recommendation of our doctors. 2016;33:118594. so this Tuesday I'll be 6 weeks and hoping I will hear a heartbeat. You will probably get a lot of responses about checking the posts at the top of the page because they remind people that hormone levels are not an indication of a pregnancy with multiples. The hCG level has to rise appropriately (it doubles every 3 days or so in early pregnancy) till it reaches around 1500 mIU/mL. Part of Subsequently, i only had one baby. They illustrated that the -t2 on day 12 after embryo transfer was about 1.6days and the cut-off value of 2.2days had an optimal PPV of 87% and an NPV of 42% [11]. Below are the average hCG levels during the first trimester: 3 weeks LMP: 5 - 50 mIU/ml 4 weeks LMP: 5 - 426 mIU/ml 5 weeks LMP: 18 - 7,340 mIU/ml In the present research, the rate of a twin pregnancy was only 5.1% (16/312) with an initial serum -hCG level<300 mIU/ml. Sung N, Kwak-Kim J, Koo HS, Yang KM. Epub 2018 May 2. HHS Vulnerability Disclosure, Help Clin Endocrinol (Oxf). Kathiresan AS, Cruz-Almeida Y, Barrionuevo MJ, Maxson WS, Hoffman DI, Weitzman VN, et al. ROC analysis showed that the predicted value for clinical pregnancy was 58.8 mIU/ml with an AUC of 0.752 (95% CI: 0.6800.823), a sensitivity of 95.0%, and a specificity of 53.5%. I had an ultrasound on 14th, they didnt see any yolk, just a tiny sac and also they confirmed that there was no ectopic pregnancy. What a relief it must be to know there are no chromosomal abnormalities. It is used to diagnose pregnancy and a result greater than 5 mIU/mL is generally considered positive. Roughly. For these reasons, it is very important to make individualized follow-up plans according to different serum -hCG intervals. I guess 5 weeks is for the natural conception. It is important to determine beta-hCG levels regardless a potential bleeding since bleeding can occur during early pregnancy. MeSH Sung et al., calculated the fold increase between post-ovulatory day 12 and day 14 in frozen-thawed cycles, but a difference between live births and early pregnancy loss was not found (3.10.9 folds vs. 3.01.0 folds; P>0.05). It does not store any personal data. A beta hCG level of over 100 is generally considered a good, positive result. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Congratulations to you. Best of luck to you too! Fold increases in -hCG concentrations over 48h were calculated by the following formula: Fold increase = \( {\left(\frac{\mathrm{HCG}1}{\mathrm{HCG}0}\right)}^{\raisebox{1ex}{$2$}\!\left/ \!\raisebox{-1ex}{$\mathrm{days}$}\right.} Most HPTs will pick up an HCG reading 11 or 12 days after the embryo enters the uterus. Days 7 and 8: Fetal development continues, and hCG continues to be secreted. Role of early serum beta human chorionic gonadotropin measurement in predicting multiple pregnancy and pregnancy wastage in an in vitro ET fertilization cycle. Epub 2020 Oct 9. I hope all goes well. Thanks for the information. This study sought to investigate pregnancy outcomes of patients with an initially low serum -hCG level at 14days after frozen blastocyst transfer. I was wondering if numbers indicate singleton or twins. Cite this article. On the contrary, an increasing frequency of abortions depending on the increasing age of the mother was once again confirmed. Whats the opinion of your doctor? 1986 Apr;45(4):526-31 Would you like email updates of new search results? Congrats on your 6 month old twin girls! An hCG level of 13,000-290, 0000 mIU/ml is reached by the end of the 1st trimester (12 weeks) whereupon it slowly declines to approximately 26,000- 300,000 mIU/ml by full term. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. The effects of low-dose human chorionic gonadotropin combined with human menopausal gonadotropin protocol on women with hypogonadotropic hypogonadism undergoing ovarian stimulation for in vitro fertilization. Nausea - Women experience morning sickness or nausea only in the second month of pregnancy, hence do not expect it during the 2-week wait after a fresh or frozen embryo transfer. Two -hCG parameters were examined in relation to live birth: 1) "doubling" defined as -hCG doubling over 48 h and 2) "reaching 100" defined as a -hCG 100 mIU/mL by 15 days after oocyte retrieval (AOR). Is it normal for after 2 weeks? You numbers are not off the charts high. Donor 21, so just did the regular genetic testing once pregnant and nuchal ultrasound. Results: One thousand three hundred forty cycles involving a single embryo were analyzed. Biochemical pregnancy loss was defined as a serum -HCG level>5mIU/ml 14days after transferring the embryo, which declined to <5 mIU/ml at the end of pregnancy without a visible gestational sac by ultrasound. -, Fertil Steril. 490 patients pregnant after IVF + ET treat-ment placed in the study. Would have been happier with one for the risk and decreased worry but after told I miscarried was so grateful to see two still on ultrasound. The https:// ensures that you are connecting to the The risk of adverse pregnancy (AP) outcomes such as ectopic pregnancy (EP), biochemical pregnancy (BP) and spontaneous abortion (SA) is greater in women undergoing ART compared with natural pregnancy. First, the patients studied had a -hCG test 14days after embryo transfer. National Library of Medicine hCG levels increased by 51% daily in both groups, but levels in ectopic pregnancies were only 14% of those from the control group on the same day (p<110-15). What are the most frequent symptoms after an embryo transfer? -, Br Med J (Clin Res Ed). Epub 2011 Nov 1. Good luck to you! At my age, I definitely need to screen for abnormalities. !..is it a miscarriage??? I'm really sorry for you . Fertil Steril. Please whitelist our site to get all the best deals and offers from our partners. When to Call Your Doctor On June 4th, my beta was 136. Most of them were biochemical pregnancies (77.8%) and the remainder were early miscarriages (13.9%) and ectopic pregnancies (8.3%). Necessary cookies are absolutely essential for the website to function properly. California Privacy Statement, It reaches its peak by 8-11 weeks of pregnancy and levels off. Objective: 2005-2023Everyday Health, Inc., a Ziff Davis company. Yohkaichiya T, Polson DW, Hughes EG, MacLachlan V, Robertson DM, Healy DL, de Kretser DM. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. CVS is a diagnostic test so it is more accurate but carries about a ..5% risk of miscarriage (1/200). My first pregnancy first hcg was 13 days after transfer and i had 2300 level. An hCG level under 5 is considered negative. Craciunas L, Tsampras N, Coomarasamy A, Raine-Fenning N. Cochrane Database Syst Rev. Among patients having a clinical pregnancy, about 60% were early miscarriage and 12.4% were ectopic pregnancy (data not shown). By continuing to browse our site you agree to our use of data and cookies. Manage cookies/Do not sell my data we use in the preference centre. If there's any concern about a high hCG level, your doctor will review the test results and discuss the next steps. MeSH Thanks for your reply. Our study showed that pregnancy outcomes of the patients with initially low serum -hCG levels were poor, with only 18.6% of live births. HCG reaches its peak level around 8 to 11 weeks after conception and levels then decline, remaining steady for the rest of the pregnancy. Stone et al., investigated the association between the doubling time of serum-borne -hCG (-t2) and ongoing pregnancy in pregnant women after assisted reproductive technology (ART). There were no statistical differences between the groups in terms of the number of embryos transferred, the protocols of endometrial preparation, days of embryo transfer and endometrial thickness. More information on the. Day 11: The embryo is surrounded by fluid inside the amniotic sac. 2011;96:13626. ktberry, your levels were 2/3 mine. I had three 5-day embryos transferred and I had just turned 43 yrs when my eggs were retrieved so it is extremely unlikely that I could be carrying twins or triplets due to the high rate of abnormal embryos in my age group. Prognostic value of beta-human chorionic gonadotropin is dependent on day of embryo transfer during invitro fertilization. Receiver operating characteristic (ROC) curves were plotted to explore the threshold of predicting clinical pregnancy and live births. Article The value in predicting live births was 1.9, with an AUC of 0.803, a sensitivity of 88.5%, a PPV of 97.4% and an NPV of 92.3%. However, this time around I am quite afraid of doing CVS. Bookshelf hCG levels chart in weeks from DPO (days past ovulation): 1 week DPO: 5 - 50 mIU/ml 2 weeks DPO: 5 - 426 mIU/ml 3 weeks DPO: 18 - 7,340 mIU/ml 4 weeks DPO: 1,080 - 56,500 mIU/ml 5 - 6 weeks DPO: 7, 650 - 229,000 mIU/ml 7 - 10 weeks DPO: 25,700 - 288,000 mIU/ml 11 - 14 weeks DPO: 13,300 - 254,000 mIU/ml 15 - 22 weeks DPO: 4,060 - 165,400 mIU/ml Delay of embryo transfer to day 5 results in decreased initial serum beta-human chorionic gonadotropin levels. Epub 2017 Oct 16. Although many previous studies have investigated the prediction of pregnancy outcomes by measuring serum -hCG levels after blastocyst transfer, no study has yet focused on pregnancy outcomes of patients with an initially low serum -hCG level. Conversely, when the hCG on day 15 was below 150 mIU/mL and the ratio of hCG on day . 5 weeks LMP: 18 - 7,340 mIU/mL. It is routine to have serum -hCG tests conducted 914days after embryo transfer to confirm the diagnosis of pregnancy. The threshold for live birth was 1.9 with an AUC of 0.808, a sensitivity of 88.5% and specificity of 64.5%. On 7th of June was 421. Human chorionic gonadotropin (hCG) is a hormone that is released by the human embryo after conception. My doctor though wants me to have another beta test(!!) Has anyone needed more HCG on top of progesterone at this stage? The measured hCG values are considerably different depending on the pregnancy result, which is why this value is considered a quality predictive factor of the pregnancy result. Fertimed, Fertility Treatment Centre, Olomouc. Initially low serum -hCG levels 14days after frozen blastocyst transfer indicated minimal chances of live birth. PubMed The probability of live birth was 63.6% if the fold increase was >1.9, as compared with the minimal likelihood of live birth (7.7%) in patients with a fold increase of <1.9. First IVF cycle on antagonist protocol (GonalF, Luveris) January 2013. If its doubling, then it means that everything is going as expected. These data support the hypothesis that hCG levels greater than 200 mIU/ml on 14 days post-ET are more likely to have ongoing pregnancies; hCG levels greater than 600 have a high likelihood of a multiple gestation pregnancy.